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Epilepsia 1993, 34: 332-346

Homologous Recombination Repair Signaling in Chemical Carcinogenesis: Prolonged Particulate Hexavallent Chromoium Exposure Suppresses the Rad51 Response in Human Lung Cells

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Protecting postmenopausal women but promoting late-stage colon cancer

Fibroblasts were preincubated with Tramenitib (10 nM, Shelleckchem), BAPTA-AM (20 M, Molecular Probes) or vehicle for 30 min before TMAO (Sigma) stimulation

This leads to a greater reliance on glycolysis, which serves to not only generate ATP but also metabolic intermediates to feed the pentose phosphate pathway